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Application of seamless capsules

Edible Capsule

Jintan probiotics capsule

Structure of 3-Layer Capsule

Acid Resistant Shell Leyer, Protective Substance Layer, Core substance, Capsule diameter: 1.0-8.0mm

Conventional problems

1. General capsule shell can hardly protect the core contents (probiotics) from the gastric acid.

2. As the result of above, most of probiotics are not able to reach the intestine alive.

Jintan's Strength

1. We guarantee the probiotics' life time wrapped in Jintan seamless capsule for 18 months in average under room temperature (*). (It may change by the types and specification of probiotics.). (*)Room temperature: 25 degree of Celsius.

2. The capsule can be delivered the ingredients to intestine directly without damage from gastoric acid.

Survival ratio of Bifidobasteria after Acid Resistance Test

Survival ratio , Hard capsule (Company A) , Hard capsule (Company B) , Oil coating , Powder , Tablet , Jintan seamless capsule , Testd by Morishita Jintan Co,.Ltd.

Pharmaceutical Capsule

Advantages of seamless capsules

  1. Variety of capsule sizes
  2. Releasing contents is designable at (1)mouth, (2)stomach, (3)intestine and (4)colon. (pH-dependent disintegration capsule patent No. JP4309045, EP1025842, US6531150, CA2307776, KR569319. / Colonic disintegration patent No.5102401, US8747893)
  3. Masking bitterness
  4. Reducing oxidation
  5. Capsule in capsule. It is able to design combination drug by patent No. JP3667045, JP5183104, EP1020177, US6426089, CA2303770, KR569488.

Excellent quality

  • ◆It has high content uniformity.
    It conforms to the standards of JP, US, EP.
  • ◆Release control is available at (1)mouth, (2)stomach and (3)intestine.

Quick soluble (oral) capsule , Capsule in capsule (Double capsule) , Enteric capsule , Colonic disintegration capsule

Sustained release ,  Dissolution test result , Disintegrator Level 1 , Disintegrator Level 2 , Disintegrator Level 3 ,  Dissolution time , Figure 1. Dissolution test results via blending difference of disintegrator including medicine  Release control by various shell formulations , Disintegration time difference for each type of shell  , Pill diameter:4.0mm Quick soluble shell , Regular shell , Masking shell , Figure 2. Oral disintegration time difference for each type of shell

Industrial capsule

Termite control

We are working on development of a termite expellant using our unique seamless capsule technology in cooperation with the research group of Graduate School of Agriculture, Kyoto University.

①Termites carry pseudo egg to their colony ②Termites take insecticide through egg grooming ③Insecticide spreads in the colony through trophallaxis ④The entire colony is disinfected by slow-acting insecticide

Others

Diverse business field as industrial utilities of Jintan seamless capsule: Construction (catalyst, curing agent, etc) / Resource (recovery, heat storage, etc) / Daily life (insecticide, cosmetics, etc) / Agriculture (artificial seed, pesticide, etc).